Exaggerated natriuretic response to atrial natriuretic factor in rats developing spontaneous hypertension.
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منابع مشابه
Exaggerated natriuretic response to atrial natriuretic factor in rats developing spontaneous hypertension.
The present study was designed to evaluate the renal response to atrial natriuretic factor (ANF) in young rats developing spontaneous hypertension (SHR) and compare this response to age-matched, normotensive controls (WKY) and adult animals. At 6 weeks of age, intravenous infusion of ANF (0.25 micrograms/kg min) in anesthetized, euvolemic rats produced a significantly larger natriuresis and diu...
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A short and up-to-date review on the great advances made in the field of the atrial natriuretic factor (ANF) is presented. All the short active peptides (up to 33 AA) isolated after purification of atrial homogenates have the same core of 23 amino acids (Ser 103-ARG 125). The ANF liberated in the medium of cultures of rat atrial cardiocytes is the 26 amino acid Arg 101-Tyr 126. Cloning of the c...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1990
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.16.1.72